CAF Champions League Predictions: African Giants Battle for Group-Stage Qualification
Steve Kay ·
Get CAF Champions League predictions for 24–25 October 2026, featuring Simba SC, Zamalek, Espérance, Pyramids FC and TP Mazembe. Explore first-leg results, qualification prospects and betting analysis.

CAF Champions League Predictions: African Giants Battle for Group-Stage Qualification
Africa's biggest club competition reaches a decisive stage this weekend as teams compete in the second legs of the CAF Champions League's second preliminary round.
With group-stage qualification at stake, several established African clubs face difficult assignments, while others have already established commanding advantages.
ChekiOdds examines the standout fixtures and the key factors to consider.
Espérance vs Swehly SC — Saturday
Four-time African champions Espérance face a difficult task after losing their first leg 1–0 to Libya's Swehly SC.
The Tunisian giants must overturn that deficit to keep their continental campaign alive.
Playing at home should provide an advantage, but Swehly have demonstrated that they can compete against more established opponents.
ChekiOdds outlook: Espérance have a realistic chance of winning the return leg, although qualification remains uncertain.
Zamalek vs APR FC — Saturday
Egyptian giants, Zamalek return home with a narrow 1–0 aggregate advantage over Rwanda's APR FC.
The visitors remain within striking distance, meaning an early goal could significantly change the complexion of the tie.
Zamalek's experience in continental competitions and home advantage put them in a favourable position.
ChekiOdds prediction: Zamalek to qualify.
Pyramids FC vs El Merriekh Bentiu — Saturday
Pyramids FC hold a 1–0 first-leg lead against South Sudan's El Merriekh Bentiu.
Although the Egyptian club are favourites to progress, a one-goal margin leaves little room for complacency.
A disciplined defensive performance and an early goal would put Pyramids in a stronger position.
ChekiOdds prediction: Pyramids FC to qualify.
RS Berkane vs Star Sport Academy — Saturday
Morocco's RS Berkane return home with a two-goal advantage after their 2–0 first-leg victory in Sierra Leone.
Their opponents now require an impressive comeback to keep the tie competitive.
Berkane have a clear opportunity to control the match and secure their place in the next round.
ChekiOdds prediction: RS Berkane to qualify.
Simba SC vs 15 de Agosto — Sunday
Tanzania's Simba SC produced one of the most convincing first-leg performances of the round, winning 6–1 away against Equatorial Guinea's 15 de Agosto.
That result places Simba in an extremely strong position to advance.
Their focus in the return fixture should be on maintaining defensive discipline and protecting their substantial advantage.
ChekiOdds prediction: Simba SC to qualify.
Club Africain vs TP Mazembe — Sunday
One of the weekend's most evenly balanced encounters features Tunisia's Club Africain against five-time continental champions TP Mazembe.
The first leg finished 1–1 in DR Congo, leaving qualification finely poised.
Club Africain have home advantage, but Mazembe's experience means the visitors cannot be discounted.
ChekiOdds outlook: Too close for a confident match-winner selection. The confirmed starting lineups and updated odds should be assessed before considering a bet.
CAF Champions League Weekend Prediction Summary
Match
First Leg
ChekiOdds Outlook
Espérance vs Swehly
Swehly 1–0 Espérance
Espérance return-leg win possible
Zamalek vs APR
APR 0–1 Zamalek
Zamalek to qualify
Pyramids vs El Merriekh Bentiu
El Merriekh 0–1 Pyramids
Pyramids to qualify
RS Berkane vs Star Sport
Star Sport 0–2 Berkane
Berkane to qualify
Simba vs 15 de Agosto
15 de Agosto 1–6 Simba
Simba to qualify
Club Africain vs TP Mazembe
TP Mazembe 1–1 Club Africain
Too close to call
African Football Weekend Verdict
The qualification picture varies considerably across the continent.
Simba, Zamalek, Pyramids and Berkane enter their matches with first-leg advantages, while Espérance and TP Mazembe have more complicated assignments.
Tanzania's Young Africans have already secured group-stage qualification following an emphatic 8–1 aggregate victory over Madagascar's CFFA.
As the remaining contenders battle for places in the group stage, ChekiOdds will continue following the biggest fixtures across African football.
Follow ChekiOdds.com for African football predictions, match analysis and bookmaker odds comparisons.
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